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Cook pasta until al dente, drain and coat lightly with olive oil. Set aside and keep warm.
In a non-stick pan, heat 2 tablespoons olive oil over medium high heat. Season salmon on all sides with half of Cajun seasoning. Sear salmon flesh side down until very browned and crispy. Flip and finish cooking (adding more oil if necessary). Remove fish to a platter, keep warm.
In same skillet, add remaining 2 tablespoons oil, onions, peppers and garlic. Season with 1 teaspoon of remaining Cajun seasoning and pinch of optional dried herbs. Sauté until soft and just beginning to brown.
Turn down heat, add alfredo sauce and half of parmesan cheese. Taste sauce and adjust seasoning by adding more Cajun seasoning, salt and herbs if desired. Sauce can also be thinned by adding a small amount of water.
Combine cooked warm pasta with sauce and place on serving dishes. Top with salmon portion (as a whole piece or flaked into pieces) and garnish with remaining cheese, parsley and lemon wedges.
This can also be made with smoked salmon (plain or flavored such as Cajun or garlic pepper), cubed fish, or other fish instead of salmon! Flake smoked salmon directly into the sauce right before serving.
Feel free to add seared sliced andouille sausage or any other seafood like shrimp, scallops or crab to this dish. Other optional ingredients could include chopped fresh or sun-dried tomatoes, peas or chopped bacon.
Try replacing the Cajun seasoning with blackening seasoning or create your own seasoning blend.